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nucleolus nu·cle·o·lus (nōō-klē'ə-ləs, nyōō-)
n. pl. nu·cle·o·li (-lī')
A small, typically round granular body composed of protein and RNA in the nucleus of a cell, usually associated with a specific chromosomal site and involved in ribosomal RNA synthesis and the formation of ribosomes.
Plural nucleoli (n-klē'ə-lī')
A small, typically spherical granular body located in the nucleus of a eukaryotic cell, composed largely of protein and RNA. When the cell is not undergoing division, loops of DNA from one or more chromosomes extend into the nucleolus and direct the synthesis of ribosomal RNA and the formation of ribosomes. The ribosomes are eventually transferred out of the nucleus via pores in the nuclear envelope into the cytoplasm.