Scleroderma

scle·ro·der·ma   (sklîr'ə-dûr'mə)    n.  A pathological thickening and hardening of the skin.

scleroderma 

Main Entry: sclero·der·ma
Pronunciation: "skler-&-'d&r-m&
Function: noun
Inflected Form: plural sclero·der·mas or sclero·der·ma·ta /-m&t-&/
: a usually slowly progressive disease marked by the deposition of fibrous connective tissue in theskin and often in internal organs and structures, by hand and foot pain upon exposure to cold, and by tightening and thickening of the skin called also dermatosclerosis

scleroderma scle·ro·der·ma (sklēr'ə-dûr'mə)
n.

1. A pathological thickening and hardening of the skin caused by swelling and thickening of fibrous tissue. Also called dermatosclerosis.

2. See progressive systemic sclerosis.

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scle'ro·der'ma·tous (-mə-təs)

scleroderma   (sklîr'ə-dûr'mə)  Pronunciation Key  A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.