| the second stage of syphilis, characterized by eruptions of the skin and mucous membrane. |

| secondary syphilis n. The second and highly infectious stage of syphilis, appearing from seven to ten weeks after the initial exposure, characterized by a general skin rash accompanied by various symptoms of illness such as fatigue, headache, sore throat, muscle pain, and fever. |
secondary syphilis n.
The second stage of syphilis, beginning with the appearance of the dermatologic eruption, slight fever, and various constitutional symptoms.