Depression is often a laborious uphill struggle for the sufferer and their loved ones.
The sufferer determines that death is the only way to cease the pain.
But many migraines come on completely mysteriously, no matter how careful a sufferer has been to avoid triggers.
early 13c., "to be made to undergo, endure" (pain, death, punishment, judgment, grief), from Anglo-French suffrir, Old French sufrir, from Vulgar Latin *sufferire, variant of Latin sufferre "to bear, undergo, endure, carry or put under," from sub "up, under" (see sub-) + ferre "to carry" (see infer).
Replaced Old English þolian, þrowian. Meaning "to meekly submit to hardship" is from late 13c. That of "to undergo" (distress, suffering, etc.) is mid-14c. Meaning "to tolerate, allow" something to occur or continue is recorded from mid-13c. Related: Suffered; suffering.