"gigantism due to activity of pituitary after normal growth has ceased," 1886, from French acromégalie, from medical Latin acromegalia, from Greek akron "extremity" (see acrid) + megas "great" (fem. megale; see mickle). Said in contemporary literature to have been coined 1885 by French physician Dr. Pierre Marie.
acromegaly ac·ro·meg·a·ly (āk'rō-měg'ə-lē)
A disorder marked by progressive enlargement of the head, face, hands, feet, and chest due to excessive secretion of growth hormone by the anterior lobe of the pituitary gland. Also called Marie's disease.