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ampicillin am·pi·cil·lin (ām'pĭ-sĭl'ĭn)
A semisynthetic of penicillin effective against gram-negative and gram-positive bacteria and used in treating infections of the intestinal, urinary, and respiratory tracts.
drug used in the treatment of various infections, including otitis media (middle ear infection), sinusitis, and acute bacterial cystitis. Ampicillin (or alpha-aminobenzylpenicillin) is a semisynthetic penicillin, one of the first such antibiotics developed. Similar in action to penicillin G but more effective against gram-negative bacteria, ampicillin is more stable in stomach acids and therefore may be given orally.