anticholinesterase

anticholinesterase

[an-tee-koh-luh-nes-tuh-reys, -reyz, -kol-uh-, an-tahy-]
noun Biochemistry, Pharmacology.
an enzyme or drug that blocks the action of acetylcholinesterase, thereby increasing the stimulating effect of acetylcholine on the muscles.

Origin:
1950–55; anti- + cholinesterase

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Based on the Random House Dictionary, © Random House, Inc. 2014.
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Collins
World English Dictionary
anticholinesterase (ˌæntɪˌkɒləˈnɛstəˌreɪz)
 
n
any of a group of substances that inhibit the action of cholinesterase

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

anticholinesterase an·ti·cho·lin·es·ter·ase (ān'tē-kō'lə-něs'tə-rās', -rāz', ān'tī-)
n.
A substance that inhibits the activity of cholinesterases, including acetylcholinesterase.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

anticholinesterase

any of several drugs that prevent destruction of the neurotransmitter acetylcholine by the enzyme acetylcholinesterase within the nervous system. Acetylcholine acts to transmit nerve impulses within the parasympathetic nervous system-i.e., that part of the autonomic nervous system that tends to induce secretion, to contract smooth muscles, and to dilate blood vessels. In preventing the destruction of acetylcholine, anticholinesterase permits high levels of this neurotransmitter to build up at the sites of its action, thus stimulating the parasympathetic nervous system and in turn slowing the heart action, lowering blood pressure, increasing secretion, and inducing contraction of the smooth muscles.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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