For men, antidepressants are roughly half as common, but that number is changing.
The exact mechanisms in the brain on which antidepressants might work to make relapse more likely are not, by any means, clear.
Mary Richardson Kennedy had three antidepressants in her system when she hanged herself.
antidepressant an·ti·de·pres·sant (ān'tē-dĭ-prěs'ənt, ān'tī-)
A drug used to prevent or relieve mental depression.
Drugs that prevent or relieve the symptoms of depression. Various psychological disorders are treated with antidepressants.
Note: Although there are many antidepressant drugs now in use, the best known is Prozac®.