[an-tee-di-pres-uhnt, an-tahy-] Pharmacology.
of or pertaining to a substance that is used in the treatment of mood disorders, as characterized by various manic or depressive affects.
Also called energizer, psychic energizer. any such substance, as a tricyclic antidepressant, MAO inhibitor, or lithium.
Also, anti-depressant, antidepressive [an-tee-di-pres-iv, an-tahy-] .

1960–65; anti- + depressant Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
antidepressant (ˌæntɪdɪˈprɛsənt)
1.  any of a class of drugs used to alleviate depression
2.  of or relating to this class of drugs

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

by 1959, from anti- + depress + adj. suffix -ant.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

antidepressant an·ti·de·pres·sant (ān'tē-dĭ-prěs'ənt, ān'tī-)
A drug used to prevent or relieve mental depression.

an'ti·de·pres'sive (-prěs'ĭv) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
antidepressant   (ān'tē-dĭ-prěs'ənt, ān'tī-)  Pronunciation Key 
A drug used to prevent or treat depression.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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American Heritage
Cultural Dictionary

antidepressants definition

Drugs that prevent or relieve the symptoms of depression. Various psychological disorders are treated with antidepressants.

Note: Although there are many antidepressant drugs now in use, the best known is Prozac®.
The American Heritage® New Dictionary of Cultural Literacy, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Example sentences for antidepressants
Other novel antidepressants specifically affect serotonin and other neurotransmitters.
Several studies have stimulated doubt about the effectiveness of antidepressants.
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