"You canker blossom!" 3 Shakespearean Insults
1680s, a nautical interjection, "hold! stop!" probably worn down from Dutch houd vast "hold fast."
AVAST. -- The order to stop, or pause, in any exercise or operation; as Avast heaving -- that is to say, desist, or stop, from drawing in the cable or hawser, by means of the capstan &c. [George Biddlecombe, "The Art of Rigging," 1848]