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city, northern seat of Mississippi county (the southern seat is Osceola), northeastern Arkansas, U.S. It lies in the Mississippi River valley, about 70 miles (113 km) north of Memphis, Tennessee. Laid out in 1880 by Henry T. Blythe, a Methodist minister, it initially had a lumber-oriented economy. After intensive logging had cleared the county's cypress and hardwood forests, the region was developed for agriculture and the processing of agricultural products. Blytheville annexed Chickasawba in 1907 and developed as the service centre for a productive cotton-growing area; soybeans, rice, and wheat are also grown there.