adjective Slang.
mentally unbalanced; mad; crazy.

1945–50; of uncertain origin; for final element, cf. -ers Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
bonkers (ˈbɒŋkəz)
slang chiefly (Brit) mad; crazy
[C20 (originally in the sense: slightly drunk, tipsy): of unknown origin]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

"crazy," 1957, British slang, perhaps from earlier naval slang meaning "slightly drunk" (1948), from notion of a thump ("bonk") on the head.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Trainers look for dogs that go bonkers over a favorite toy, such a tennis ball.
But they're bonkers when it comes to giving sanctuary.
The sleeper parched of his dreams, or purged of his nightmares, goes swiftly
  bonkers: without fantasy there is no reality.
They're not all that interested in that, except when it's time to film, and
  then they go bonkers.
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