Those into “robo-tripping” often just chug the medicine without any chaser at all.
On the nights before drill, a couple of adult beverages and an Ambien chaser usually did the trick.
Then she poured Milk of Magnesia into the other glass as a chaser.
c.1300, "horse trained for chasing," agent noun from chase (v.), probably in some cases from Old French chaceor "huntsman, hunter." Meaning "water or mild beverage taken after a strong drink" is 1897, U.S. colloquial. French had chasse (from chasser "to chase") "a drink of liquor taken (or said to be taken) to kill the aftertaste of coffee or tobacco," used in English from c.1800.