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chlorpromazine chlor·prom·a·zine (klôr-prŏm'ə-zēn', -prō'mə-)
A phenothiazine antipsychotic agent with antiemetic, antiadrenergic, and anticholinergic actions.
potent synthetic tranquilizing drug that acts selectively upon the higher centres in the brain as a depressant of the central nervous system. It is used in the treatment of persons with psychotic disorders. Chlorpromazine was first synthesized in 1950 and became generally available for medical use in the mid-1950s. One of the first tranquilizers introduced into medicine-along with the rauwolfia alkaloid, reserpine-chlorpromazine soon displaced reserpine in psychiatric practice.