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[si-truh-leen] /ˈsɪ trəˌlin/
noun, Biochemistry
an amino acid, NH 2 CONH(CH 2) 3 CHNH 2 COOH, abundant in watermelons and an intermediate compound in the urea cycle.
Origin of citrulline
1930; < New Latin citrull(us) the watermelon genus (Medieval Latin citrul(l)us, citrolus, Latinization of South Italian citrulo, Tuscan citri(u)olo < Late Latin citrium watermelon (derivative of Latincitrus (see citrus); apparently in reference to the citroncolored fruit of some types of watermelon), with -uolo < Latin -eolus) + -ine2 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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British Dictionary definitions for citrulline


an amino acid that occurs in watermelons and is an intermediate in the formation of urea. Formula: NH2CONH(CH2)3CHNH2COOH
Word Origin
C20: from Medieval Latin citrullus a kind of watermelon, from Latin citron, referring to its colour
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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citrulline in Medicine

citrulline cit·rul·line (sĭt'rə-lēn')
An amino acid produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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citrulline in Science
An amino acid originally isolated from watermelon, occurring mostly in the liver as an intermediate in the conversion of ornithine to arginine during urea formation. Chemical formula: C6H13N3O3.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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