Clarksdale
city, seat (1892) of Coahoma county, northwestern Mississippi, U.S. It is situated in the Mississippi River valley and lies along the Sunflower River, about 75 miles (120 km) south-southwest of Memphis, Tennessee. It was settled in 1848 by John Clark on a Native American fortification site; in 1868 he opened a store and laid out a village, which was originally named Clarksville
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