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A soft, nonrigid, insoluble mass formed when blood or lymph gels. v. clot·ted, clot·ting, clots
A soft insoluble mass formed when blood or lymph gels. During blood clotting, white blood cells, red blood cells, platelets, and various clotting factors interact in a cascade of chemical reactions initiated by a wound. When a body tissue is injured, calcium ions and platelets act on prothrombin to produce the enzyme thrombin. Thrombin then catalyzes the conversion of the protein fibrinogen into fibrin, a fibrous protein that holds the clot together. An abnormal clot inside the blood vessels or the heart (a thrombus or an embolus) can obstruct blood flow.