verb (used with object), verb (used without object), curdled, curdling.
to change into curd; coagulate; congeal.
to spoil; turn sour.
to go wrong; turn bad or fail: Their friendship began to curdle as soon as they became business rivals.
curdle the/one's blood, to fill a person with horror or fear; terrify: a scream that curdled the blood.

1580–90; curd + -le

curdler, noun
noncurdling, adjective, noun
uncurdled, adjective
uncurdling, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
curdle (ˈkɜːdəl)
1.  to turn or cause to turn into curd
2.  curdle someone's blood to fill someone with fear
[C16 (crudled, past participle): from curd]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

c.1630 (earlier crudle, 1580s), "to thicken, cause to congeal," frequentative of curd (v.) "to make into curd" (late 14c.; see curd). Of blood, in fig. sense "to inspire horror" from c.1600. Related: Curdled (1590); curdling (c.1700, almost always with ref. to blood, in the figurative sense).
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Fresh warm milk is an ideal food for many kinds of bacteria, especially the
  common one which causes milk to sour and curdle.
Because bacteria slowly sour milk, old milk may be acidic enough to curdle
  instantly when added to hot coffee or tea.
Anger and frustration curdle in rival political camps, fed by a partisan press.
Do not allow sauce to boil or egg yolks will curdle.
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