1545, first element obscure, second element is Northumbrian or E. Anglian dial. huff, hurf "scab," from O.N. hrufa, from P.Gmc. *hreufaz, source of O.E. hreofla "leper."
Main Entry: dan·druff Pronunciation: 'dan-dr&f Function: noun : a scurf that forms on the skin especially of the scalp and comes off in smallwhite or grayish scales —dan·druffy/-E/adjective