death·blow

[deth-bloh]
noun
a blow causing death.

Origin:
1785–95; death + blow1

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Based on the Random House Dictionary, © Random House, Inc. 2013.
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World English Dictionary
deathblow (ˈdɛθˌbləʊ) [Click for IPA pronunciation guide]
 
n
a thing or event that destroys life or hope, esp suddenly

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
Cite This Source
00:10
Deathblow is always a great word to know.
So is doohickey. Does it mean:
an arrangement of five objects, as trees, in a square or rectangle, one at each corner and one in the middle.
a gadget; dingus; thingumbob.
Example sentences
The result was a near deathblow to the industry, which was frozen in place for
  decades.
The deathblow is delivered with a quick thrust of the sharp bill, and the prey
  is swallowed whole.
Despite the help that poured in during the following weeks, residents feared
  that their town had suffered a deathblow.
Nuclear power's success was short-lived and it suffered a near deathblow from
  the combination of several events.
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