degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv]
adjective
1.
tending to degenerate.
2.
characterized by degeneration.

Origin:
1840–50; degenerate + -ive

nondegenerative, adjective
undegenerative, adjective
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Collins
World English Dictionary
degenerative (dɪˈdʒɛnəˌreɪtɪv)
 
adj
(of a disease or condition) getting steadily worse

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Etymonline
Word Origin & History

degenerative
from L. degenerat-, pp. stem of degenerare (see degenerate) + -ive.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

degenerative de·gen·er·a·tive (dĭ-jěn'ər-ə-tĭv)
adj.
Of, relating to, causing, or characterized by degeneration.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
Alzheimer's disease is a degenerative illness of the brain.
But the list of ailments that are being worked on leans towards the chronic,
  expensive degenerative diseases of old age.
We also will turn genes on and off to treat cancer, as well as auto-immune and
  other degenerative diseases.
They do not seem to suffer from degenerative bone loss or muscle cramping
  despite months spent in small quarters.
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