verb (used with object), dehydrated, dehydrating.
to deprive (a chemical compound) of water or the elements of water.
to free (fruit, vegetables, etc.) from moisture for preservation; dry.
to remove water from (the body or a tissue).
to deprive of spirit, force, or meaning; render less interesting or effectual.
verb (used without object), dehydrated, dehydrating.
to lose water or moisture: Milk dehydrates easily.

1850–55; de- + hydrate

2. See evaporate. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
dehydrate (diːˈhaɪdreɪt, ˌdiːhaɪˈdreɪt)
1.  to lose or cause to lose water; make or become anhydrous
2.  to lose or cause to lose hydrogen atoms and oxygen atoms in the proportions in which they occur in water, as in a chemical reaction
3.  to lose or deprive of water, as the body or tissues

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1854, from Gk. hydor "water" (see water (n.1)). A chemical term at first, given a broader extension 1880s. Related: Dehydration (1834).
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

dehydrate (dē-hī'drāt')
v. de·hy·drat·ed, de·hy·drat·ing, de·hy·drates

  1. To remove water from; make anhydrous.

  2. To preserve by removing water from something, such as vegetables.

  3. To deplete the bodily fluids of an individual.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
But avoid alcoholic drinks, coffee or soda because they can dehydrate you.
The yellow substance was gypsum, or calcium sulfate dehydrate, a common
  component of plaster.
Freezing organs isn't an option, as the cells dehydrate.
But if you're drinking too much alcohol or caffeine and not enough water or
  other liquids, you can dehydrate.
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