"You canker blossom!" 3 Shakespearean Insults
early 15c., from Middle French dentifrice (15c.), from Latin dentifricium "powder for rubbing the teeth," from dens (genitive dentis) "tooth" (see tooth) + fricare "to rub" (see friction).
dentifrice den·ti·frice (děn'tə-frĭs')n. A substance, such as a paste or powder, for cleaning the teeth.