the act of deranging.
disarrangement; disorder.

1730–40; < French dérangement. See derange, -ment Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
derangement (dɪˈreɪndʒmənt)
1.  the act of deranging or state of being deranged
2.  disorder or confusion
3.  psychiatry a mental disorder or serious mental disturbance

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

1737, "disturbance of regular order," from Fr. dérangement (17c.), from déranger (see derange). Of mental order, from 1800.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

derangement de·range·ment (dĭ-rānj'mənt)

  1. Disturbance of the regular order or arrangement of parts in a system.

  2. Mental disorder; insanity.

de·range' v.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
My husband favored me with a sigh suggesting that the family had long noted my
With great trials were mingled petty inconveniences arising from derangement of
  the country's finances.
Notwithstanding the acute apprehension and general derangement of affairs,
  there was nothing resembling panic.
Half a century ago, when people talked about anti-white racism, it was often
  depicted as a symptom of a broader derangement.
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