Main Entry: de·si·pra·mine Pronunciation: "dez-&-'pram-&n, d&-'zip-r&-"mEn Function: noun : a tricyclic antidepressantC18H22N2 administered in the form of its hydrochloride especially in the treatment of endogenous depressions (as a bipolar disorder) —see NORPRAMIN, PERTOFRANE