[dis-uhd-van-tij, -vahn-]
absence or deprivation of advantage or equality.
the state or an instance of being in an unfavorable circumstance or condition: to be at a disadvantage.
something that puts one in an unfavorable position or condition: His bad temper is a disadvantage.
injury to interest, reputation, credit, profit, etc.; loss: Your behavior is a disadvantage to your family's good name.
verb (used with object), disadvantaged, disadvantaging.
to subject to disadvantage: I was disadvantaged by illness.

1350–1400; Middle English disavauntage < Anglo-French; Old French desavantage. See dis-1, advantage

1. drawback, inconvenience, hindrance. 4. detriment, hurt, harm, damage.
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World English Dictionary
disadvantage (ˌdɪsədˈvɑːntɪdʒ)
1.  an unfavourable circumstance, state of affairs, thing, person, etc
2.  injury, loss, or detriment
3.  an unfavourable condition or situation (esp in the phrase at a disadvantage)
4.  (tr) to put at a disadvantage; handicap

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

late 14c., from Fr. desavantage (13c.); see dis- + advantage. The verb is attested from 1530s, from the noun.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
The researchers emphasize, however, that their findings do not mean that
  left-handed people are at a biological disadvantage.
It isn't a bug enough disadvantage to spend a ton of money going somewhere
  else, tho.
One disadvantage of water spouts is that they can be torn apart by the wind.
There is no disadvantage in this case to economize on file size.
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