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endogenous depression

noun, Psychiatry.
a severe form of depression usually characterized by insomnia, weight loss, and inability to experience pleasure, thought to be of internal origin and not influenced by external events.
Also called melancholia.
Origin of endogenous depression
1960-65 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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endogenous-depression in Medicine

endogenous depression n.
A group of symptoms that resemble depression but are not precipitated by a stressful experience, especially psychomotor agitation or retardation, insomnia and early morning awakening, weight loss, excessive guilt, and a lack of reactivity to one's environment.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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