Biochemistry. an estrogenic hormone, C 18 H 22 O 2 , produced by the ovarian follicles and found during pregnancy in urine and placental tissue.
Pharmacology. a commercial form of this compound, obtained from the urine of pregnant women or synthesized from ergosterol, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.
Also, estrin.

1930–35; estr(in) + -one Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
estrone (ˈɛstrəʊn, ˈiːstrəʊn)
the usual US spelling of oestrone

oestrone or (US) estrone (ˈiːstrəʊn, ˈɛstrəʊn)
a weak oestrogenic hormone secreted by the mammalian ovary and having the same medical uses as oestradiol. Formula: C18H22O2
[C20: from oestr(us) + -one]
estrone or (US) estrone
[C20: from oestr(us) + -one]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

estrone es·trone (ěs'trōn')
A metabolite of estradiol, commonly found in urine, having considerably less biological activity than estradiol but similar properties and uses. Also called theelin.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
The other important, but less powerful, estrogens are estrone and estriol.
The other important but less powerful estrogens are estrone and estriol.
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