exasperation

[ig-zas-puh-rey-shuhn]
noun
1.
an act or instance of exasperating; provocation.
2.
the state of being exasperated; irritation; extreme annoyance: Her exasperation at being interrupted was understandable.

Origin:
1540–50; < Latin exasperātiōn- (stem of exasperātiō) roughness, bitterness. See exasperate, -ion

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World English Dictionary
exasperate (ɪɡˈzɑːspəˌreɪt)
 
vb
1.  to cause great irritation or anger to; infuriate
2.  to cause (an unpleasant feeling, condition, etc) to worsen; aggravate
 
adj
3.  botany having a rough prickly surface because of the presence of hard projecting points
 
[C16: from Latin exasperāre to make rough, from asper rough]
 
ex'asperatedly
 
adv
 
ex'asperater
 
n
 
ex'asperating
 
adj
 
ex'asperatingly
 
adv
 
exasper'ation
 
n

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Etymonline
Word Origin & History

exasperation
1540s, from L. exasperationem, noun of action from exasperare (see exasperate).
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
In exasperation he took off his own hat and flung it to the ground.
There's a sort of easygoing tolerance of others, but it's often spiked with
  insult and exasperation.
The reason for my exasperation is that I do not believe the current job system
  can ever lend itself to statistical analysis.
Adriana threw up her hands in exasperation.
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