noun, plural -li⋅os, adjective, verb, -li⋅oed, -li⋅o⋅ing.| 1. | a sheet of paper folded once to make two leaves, or four pages, of a book or manuscript. |
| 2. | a volume having pages of the largest size, formerly made from such a sheet. |
| 3. | a leaf of a manuscript or book numbered only on the front side. |
| 4. | Printing.
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| 5. | Bookkeeping. a page of an account book or a left-hand page and a right-hand page facing each other and having the same serial number. |
| 6. | Law. a certain number of words, in the U.S. generally 100, taken as a unit for computing the length of a document. |
| 7. | pertaining to or having the format of a folio: a folio volume. |
| 8. | to number each leaf or page of. |
| 9. | Law. to mark each folio in (a pleading or the like) with the proper number. |
folio