a little grain.
a small particle; pellet.
a corpuscle; sporule.

1645–55; < Late Latin grānulum small grain. See grain, -ule

boulder, cobblestone, granule, pebble, rock, stone. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
granule (ˈɡrænjuːl)
1.  a small grain
2.  geology a single rock fragment in gravel, smaller than a pebble but larger than a sand grain
3.  astronomy another name for granulation
[C17: from Late Latin grānulum a small grain]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

granule gran·ule (grān'yōōl)

  1. A small grain or pellet; a particle.

  2. A cellular or cytoplasmic particle, especially one that stains readily.

  3. A very small pill, usually coated with gelatin or sugar.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
granule   (grān'yl)  Pronunciation Key 
  1. A rock or mineral fragment larger than a sand grain and smaller than a pebble. Granules have a diameter between 2 and 4 mm (0.08 and 0.16 in) and are often rounded.

  2. Any of the small, transient convective cells within the Sun's photosphere where hot gases rise and quickly dissipate. Granules are generally between a few hundred and 1,500 km in width. They completely cover the Sun's surface, giving it its characteristic grainy or stippled look, and form and break up within a matter of minutes.

  3. An aggregate of enclosed grainy matter found in a cell. Granulocytes, mast cells and other cells contain granules in their cytoplasm, which differ in size and can often be identified by a characteristic laboratory stain based on their composition. Granules produce and store biologically active substances, the release of which is called degranulation. The granules of granulocytes contain mostly multiple enzymes and other proteins; those of mast cells contain histamine and other chemical mediators.

The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
The granule is characterised by its internal acidity, a high electron density and a specialised surrounding membrane.
In modern birds pigments in feathers come in small granules, and the granule for each color has a different shape.
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