emotional pain or distress; sorrow; grief; anguish.

before 1000; Middle English hert ache, Old English heort ece; see heart, ache

heartaching, adjective
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
heartache (ˈhɑːtˌeɪk)
intense anguish or mental suffering

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

O.E. in the sense of a physical pain, c.1600 in sense of "anguish of mind;" from heart + ache. O.E. did, however, have heartsarnes "grief," lit. "heart-soreness."
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Usually they are sick for a long time, months of sorrow and heartache.
But, billions of dollars and much heartache later, it is ready.
But now it's gathering dust, and maybe even causing you heartache.
Challenge and criticism produces nothing but heartache.
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