Biochemistry. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid.
Pharmacology. a commercial form of this substance, used chiefly to promote the diffusion of intradermally injected drugs.
hyaluronidase hy·a·lu·ron·i·dase (hī'ə-lu-rŏn'ĭ-dās', -dāz') n. Any of three enzymes that catalyze the hydrolysis of hyaluronic acid, thus increasing tissue permeability to fluids. One or more of these enzymes occur in the testes and in spermatozoa.