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hyaluronidase hy·a·lu·ron·i·dase (hī'ə-lu-rŏn'ĭ-dās', -dāz')
Any of three enzymes that catalyze the hydrolysis of hyaluronic acid, thus increasing tissue permeability to fluids. One or more of these enzymes occur in the testes and in spermatozoa.
any of a group of enzymes that catalyze the hydrolysis (chemical decomposition involving the elements of water) of certain complex carbohydrates such as hyaluronic acid and chondroitin sulfates. The enzymes have been found in insects, leeches, snake venom, mammalian tissues (testis being the richest mammalian source), and in bacteria.