[hahy-uh-loo-ron-i-deys, -deyz]
Biochemistry. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid.
Pharmacology. a commercial form of this substance, used chiefly to promote the diffusion of intradermally injected drugs.

1935–40; hyaluron(ic) + -id- (by analogy with amidase, peptidase, etc.) + -ase

Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
Cite This Source Link To hyaluronidase
World English Dictionary
hyaluronidase (ˌhaɪəlʊˈrɒnɪˌdeɪs, -ˌdeɪz)
an enzyme that breaks down hyaluronic acid, thus decreasing the viscosity of the medium containing the acid
[C20: hyalo- + Greek ouron urine + -id³ + -ase]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
Cite This Source
American Heritage
Medical Dictionary

hyaluronidase hy·a·lu·ron·i·dase (hī'ə-lu-rŏn'ĭ-dās', -dāz')
Any of three enzymes that catalyze the hydrolysis of hyaluronic acid, thus increasing tissue permeability to fluids. One or more of these enzymes occur in the testes and in spermatozoa.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
Cite This Source
Encyclopedia Britannica


any of a group of enzymes that catalyze the hydrolysis (chemical decomposition involving the elements of water) of certain complex carbohydrates such as hyaluronic acid and chondroitin sulfates. The enzymes have been found in insects, leeches, snake venom, mammalian tissues (testis being the richest mammalian source), and in bacteria.

Learn more about hyaluronidase with a free trial on Britannica.com.

Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
Cite This Source
Copyright © 2014 Dictionary.com, LLC. All rights reserved.
  • Please Login or Sign Up to use the Recent Searches feature