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hyaluronidase

[hahy-uh-loo-ron-i-deys, -deyz] /ˌhaɪ ə lʊˈrɒn ɪˌdeɪs, -ˌdeɪz/
noun
1.
Biochemistry. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid.
2.
Pharmacology. a commercial form of this substance, used chiefly to promote the diffusion of intradermally injected drugs.
Origin
1935-1940
1935-40; hyaluron(ic) + -id- (by analogy with amidase, peptidase, etc.) + -ase
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for hyaluronidase

hyaluronidase

/ˌhaɪəlʊˈrɒnɪˌdeɪs; -ˌdeɪz/
noun
1.
an enzyme that breaks down hyaluronic acid, thus decreasing the viscosity of the medium containing the acid
Word Origin
C20: hyalo- + Greek ouron urine + -id³ + -ase
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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hyaluronidase in Medicine

hyaluronidase hy·a·lu·ron·i·dase (hī'ə-lu-rŏn'ĭ-dās', -dāz')
n.
Any of three enzymes that catalyze the hydrolysis of hyaluronic acid, thus increasing tissue permeability to fluids. One or more of these enzymes occur in the testes and in spermatozoa.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Article for hyaluronidase

any of a group of enzymes that catalyze the hydrolysis (chemical decomposition involving the elements of water) of certain complex carbohydrates such as hyaluronic acid and chondroitin sulfates. The enzymes have been found in insects, leeches, snake venom, mammalian tissues (testis being the richest mammalian source), and in bacteria.

Learn more about hyaluronidase with a free trial on Britannica.com
Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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