Quiz: Remember the definition of mal de mer?


[hahy-uh-loo-ron-i-deys, -deyz] /ˌhaɪ ə lʊˈrɒn ɪˌdeɪs, -ˌdeɪz/
Biochemistry. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid.
Pharmacology. a commercial form of this substance, used chiefly to promote the diffusion of intradermally injected drugs.
1935-40; hyaluron(ic) + -id- (by analogy with amidase, peptidase, etc.) + -ase Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
Cite This Source
British Dictionary definitions for hyaluronidase


/ˌhaɪəlʊˈrɒnɪˌdeɪs; -ˌdeɪz/
an enzyme that breaks down hyaluronic acid, thus decreasing the viscosity of the medium containing the acid
Word Origin
C20: hyalo- + Greek ouron urine + -id³ + -ase
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
Cite This Source
hyaluronidase in Medicine

hyaluronidase hy·a·lu·ron·i·dase (hī'ə-lu-rŏn'ĭ-dās', -dāz')
Any of three enzymes that catalyze the hydrolysis of hyaluronic acid, thus increasing tissue permeability to fluids. One or more of these enzymes occur in the testes and in spermatozoa.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
Cite This Source
Encyclopedia Article for hyaluronidase

any of a group of enzymes that catalyze the hydrolysis (chemical decomposition involving the elements of water) of certain complex carbohydrates such as hyaluronic acid and chondroitin sulfates. The enzymes have been found in insects, leeches, snake venom, mammalian tissues (testis being the richest mammalian source), and in bacteria.

Learn more about hyaluronidase with a free trial on
Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
Cite This Source

Word of the Day

Difficulty index for hyaluronidase

Few English speakers likely know this word

Word Value for hyaluronidase

Scrabble Words With Friends