hydroxyproline

hydroxyproline

[hahy-drok-si-proh-leen, -lin]
noun Biochemistry.
a nutritionally nonessential amino acid, C 5 H 9 NO 3 , found chiefly in collagen.

Origin:
1900–05; hydroxy- + proline

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Collins
World English Dictionary
hydroxyproline (haɪˌdrɒksɪˈprəʊliːn, -lɪn)
 
n
an amino acid occurring in some proteins, esp collagen. Formula: (OH)C4H7N(COOH)

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

hydroxyproline hy·drox·y·pro·line (hī-drŏk'sē-prō'lēn')
n.
An amino acid produced during the hydrolysis of collagen.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

hydroxyproline

an amino acid formed upon hydrolysis of connective-tissue proteins such as collagen (about 14 percent by weight) and elastin but rarely from other proteins. The molecular structure of hydroxyproline contains a secondary amino group (NH) rather than the primary amino group (-NH2) characteristic of most amino acids. First isolated (1902) from gelatin, a breakdown product of collagen, hydroxyproline is one of several so-called nonessential amino acids; i.e., animals can synthesize it from glutamic acid and do not require dietary sources. Excretion of abnormal quantities of hydroxyproline is a symptom of the connective-tissue disease called Marfan's syndrome.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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