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[hahy-drok-si-proh-leen, -lin] /haɪˈdrɒk sɪˈproʊ lin, -lɪn/
noun, Biochemistry
a nutritionally nonessential amino acid, C 5 H 9 NO 3 , found chiefly in collagen.
1900-05; hydroxy- + proline Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for hydroxyproline


/haɪˌdrɒksɪˈprəʊliːn; -lɪn/
an amino acid occurring in some proteins, esp collagen. Formula: (OH)C4H7N(COOH)
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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hydroxyproline in Medicine

hydroxyproline hy·drox·y·pro·line (hī-drŏk'sē-prō'lēn')
An amino acid produced during the hydrolysis of collagen.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Article for hydroxyproline

an amino acid formed upon hydrolysis of connective-tissue proteins such as collagen (about 14 percent by weight) and elastin but rarely from other proteins. The molecular structure of hydroxyproline contains a secondary amino group (NH) rather than the primary amino group (-NH2) characteristic of most amino acids. First isolated (1902) from gelatin, a breakdown product of collagen, hydroxyproline is one of several so-called nonessential amino acids; i.e., animals can synthesize it from glutamic acid and do not require dietary sources. Excretion of abnormal quantities of hydroxyproline is a symptom of the connective-tissue disease called Marfan's syndrome.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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