"You canker blossom!" 3 Shakespearean Insults
1550s, from Spanish, from Arawakan (W.Indies) iguana, iwana, the local name for the lizard.
Foure footed beastes ... named Iuannas, muche lyke vnto Crocodiles, of eyght foote length, of moste pleasaunte taste. [Richard Eden, "Decades of the New World," 1555]