verb (used with object)
to live in or overrun to an unwanted degree or in a troublesome manner, especially as predatory animals or vermin do: Sharks infested the coastline.
to be numerous in, as anything undesirable or troublesome: the cares that infest the day.
Archaic. to harass.

1375–1425; late Middle English < Latin infestāre to assail, molest, derivative of infestus hostile

infester, noun
reinfest, verb (used with object)
uninfested, adjective

infect, infest, invest. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
infest (ɪnˈfɛst)
1.  to inhabit or overrun in dangerously or unpleasantly large numbers
2.  (of parasites such as lice) to invade and live on or in (a host)
[C15: from Latin infestāre to molest, from infestus hostile]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

late 15c., "to attack, assail, hurt, distress, annoy," from M.Fr. infester, from L. infestare "to attack, disturb, trouble," from infestus "hostile, dangerous," originally "inexorable, not able to be handled," from in- "not" + -festus "(able to be) seized." Sense of "swarm over in large numbers" first
recorded c.1600.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

infest in·fest (ĭn-fěst')
v. in·fest·ed, in·fest·ing, in·fests

  1. To live as a parasite in or on tissues or organs or on the skin and its appendages.

  2. To inhabit or overrun in numbers large enough to be harmful, threatening, or obnoxious.

in'fes·ta'tion n.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
And spam messages and infectious postings continue to infest social networks.
We see no end of these large-children gaffing up our society as they infest
  politics and other social organizations.
While many trees affected by borers have been stressed or diseased, they will
  also infest healthy trees.
The ability of termites to find, infest, and feed upon wood after it had been
  charred was evaluated in the laboratory and field.
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