without regard to something else, especially something specified; ignoring or discounting (usually followed by of ): Irrespective of my wishes, I should go.

1630–40; ir-2 + respective

irrespectively, adverb Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
irrespective (ˌɪrɪˈspɛktɪv)
1.  (preposition) irrespective of without taking account of; regardless of
2.  informal regardless; without due consideration: he carried on with his plan irrespective

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Example sentences
It is a mortal sin to use the tax word irrespective of the cause or worthiness
  of the need.
Courage remains a virtue irrespective of its physiological basis.
Which means some people who take them will not be people who should be in
  college, irrespective of their financial status.
What is more, voters seem to be picking and choosing among the candidates
  irrespective of party affiliation.
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