isolative

[ahy-suh-ley-tiv, is-uh-]
adjective
noting a change in part of the sound of a word made independently of the phonetic environment of that part.

Origin:
1885–90; isolate + -ive

unisolative, adjective
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World English Dictionary
isolative (ˈaɪsəˌleɪtɪv, ˈaɪsələtɪv)
 
adj
1.  Compare combinative (of a sound change) occurring in all linguistic environments, as the change of Middle English // to Modern English //, as in time
2.  of, relating to, or concerned with isolation

Collins English Dictionary - Complete & Unabridged 10th Edition
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Example sentences
Drug use of any kind eventually becomes isolative and self centered.
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