an act or instance of knocking out.
the state or fact of being knocked out.
a knockout blow.
Informal. a person or thing overwhelmingly attractive, appealing, or successful.
a panel in a casing, can, or box, especially of metal or plastic, so designed that it can readily be removed, as by punching, hammering, or cutting, to provide an opening into the interior: a knockout in a junction box.
Machinery. a device for knocking something loose, as finished work from a lathe chuck.
that knocks out: the knockout punch.

1810–20; 1935–40 for def 4; noun, adj. use of verb phrase knock out Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
knockout (ˈnɒkˌaʊt)
1.  the act of rendering unconscious
2.  a blow that renders an opponent unconscious
3.  a.  a competition in which competitors are eliminated progressively
 b.  (as modifier): a knockout contest
4.  a series of absurd invented games, esp obstacle races, involving physical effort or skill
5.  informal a person or thing that is overwhelmingly impressive or attractive: she's a knockout
6.  to render unconscious, esp by a blow
7.  boxing to defeat (an opponent) by a knockout
8.  to destroy, damage, or injure badly
9.  to eliminate, esp in a knockout competition
10.  informal to overwhelm or amaze, esp with admiration or favourable reaction: I was knocked out by that new song
11.  to remove the ashes from (one's pipe) by tapping

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Example sentences
One of the knockout pieces on display is of one of the more recognizable people
  in the struggle for civil rights.
The diabetic mouse model has not always translated well to humans, and commonly
  used knockout mice represent an extreme condition.
And the knockout punch is finding out that he's not real at all.
Before long, the knockout mice began developing curious lesions around their
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