a person who has leprosy.
a person who has been rejected or ostracized for unacceptable behavior, opinions, character, or the like; anathema; outcast.

1350–1400; Middle English lepre leprosy < Latin lepra < Greek lépra, noun use of feminine of leprós scaly, akin to lépos scale, lépein to peel

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World English Dictionary
leper (ˈlɛpə)
1.  a person who has leprosy
2.  a person who is ignored or despised
[C14: via Late Latin from Greek lepra, noun use of lepros scaly, from lepein to peel]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

"one afflicted with leprosy," late 14c., from L.L. lepra, from Gk. lepra "leprosy," from fem. of lepros (adj.) "scaly," from leops "a scale," related to lepein "to peel," from lopos "a peel," from PIE base *lep- "to peel, scale" (see leaf). Originally the word for the disease
itself (mid-13c.); because of the -er ending it came to mean "person with leprosy," so leprosy was coined 16c. from adj. leprous.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

leper lep·er (lěp'ər)
One who has leprosy.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
In his own heroic way, he refused to be the great celebrity leper.
Quite simply it is a leper that western corporations are desperate to keep away from in case their image is infected.
Researchers say that the ancient leper provides clues to how the disease spread through the human population.
She speaks wistfully of a long-abandoned plan to work in a leper colony, and before the end of the novel she gets her wish.
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