lifework

[lahyf-wurk]
noun
the complete or principal work, labor, or task of a lifetime.

Origin:
1870–75; life + work

Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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Example sentences
The introducer explained that my research had disproved part of my adviser's lifework, and the shock had killed him.
It was unusual then for people their age to be unattached, no matter how important their lifework.
These skills are fundamental to lifework planning and lifelong learning.
It is also being used with adults who want to clarify their lifework objectives and perhaps make mid-life career changes.
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