Is it farther or further?
Old English losian "be lost, perish," from los "destruction, loss," from Proto-Germanic *lausa- (cf. Old Norse los "the breaking up of an army;" Old English forleosan "to lose, destroy," Old Frisian forliasa, Old Saxon farliosan, Middle Dutch verliesen, Old High German firliosan, German verlieren), from PIE root *leu- "to loosen, divide, cut apart, untie, separate" (cf. Sanskrit lunati "cuts, cuts off," lavitram "sickle;" Greek lyein "to loosen, untie, slacken," lysus "a loosening;" Latin luere "to loose, release, atone for, expiate").
Replaced related leosan (a class II strong verb whose past participle loren survives in forlorn and lovelorn), from Proto-Germanic *leusanan (cf. Old High German virliosan, German verlieren, Old Frisian urliasa, Gothic fraliusan "to lose").
Transitive sense of "to part with accidentally" is from c.1200. Meaning "fail to maintain" is from mid-15c. Meaning "to be defeated" (in a game, etc.) is from 1530s. Meaning "to cause (someone) to lose his way" is from 1640s. To lose (one's) mind "become insane" is attested from c.1500. To lose out "fail" is 1858, American English. Related: Lost; losing.
(MIT) 1. To fail. A program loses when it encounters an exceptional condition or fails to work in the expected manner.
2. To be exceptionally unesthetic or crocky.
3. Of people, to be obnoxious or unusually stupid (as opposed to ignorant).
4. Refers to something that is losing, especially in the phrases "That's a lose!" and "What a lose!"