"a destroyer," mid-14c., from lose (q.v.). Sense of "one who suffers loss" is from 1540s; meaning "horse that loses a race" is from 1902; "convicted criminal" is from 1912; "hapless person" is 1955 student slang.
n. an inept person; an undesirable or annoying person; a social failure. : Those guys are all losers. They'll never amount to anything.
Dictionary of American Slang and Colloquial Expressions by Richard A. Spears.Fourth Edition. Copyright 2007. Published by McGraw Hill.
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loser definition
jargon An unexpectedly bad situation, program, programmer, or person. Someone who habitually loses. (Even winners can lose occasionally). Someone who knows not and knows not that he knows not. Emphatic forms are "real loser", "total loser", and "complete loser" (but not **"moby loser", which would be a contradiction in terms). See luser. [Jargon File] (1995-04-19)