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c.1300, maleise "pain, suffering; sorrow, anxiety," also, by late 14c., "disease, sickness," from Old French malaise "difficulty, suffering, hardship," literally "ill-ease," from mal "bad" (see mal-) + aise "ease" (see ease (n.)). The current use is perhaps a mid-18c. reborrowing from Modern French. A Middle English verbal form, malasen "to trouble, distress" (mid-15c.), from Old French malaisier, did not endure.
malaise mal·aise (mā-lāz', -lěz')
A vague feeling of bodily discomfort, as at the beginning of an illness.