the making of goods or wares by manual labor or by machinery, especially on a large scale: the manufacture of television sets.
the making or producing of anything; generation: the manufacture of body cells.
the thing or material manufactured; product: Plastic is an important manufacture.
verb (used with object), manufactured, manufacturing.
to make or produce by hand or machinery, especially on a large scale.
to work up (material) into form for use: to manufacture cotton.
to invent fictitiously; fabricate; concoct: to manufacture an account of the incident.
to produce in a mechanical way without inspiration or originality: to manufacture a daily quota of poetry.

1560–70; obsolete manufact (see manufactory) + -ure

manufacturable, adjective
manufactural, adjective
nonmanufacture, noun
nonmanufactured, adjective
nonmanufacturing, noun
premanufacture, verb (used with object), premanufactured, premanufacturing.
semimanufactured, adjective
semimanufacturing, noun
unmanufacturable, adjective
unmanufactured, adjective
well-manufactured, adjective

4. build. Manufacture, assemble, fabricate apply to processes in industry. Manufacture originally to make by hand, now means to make by machine or by industrial process: to manufacture rubber tires. To assemble is to fit together the manufactured parts of something mechanical: to assemble an automobile. To fabricate is to construct or build by fitting standardized parts together: to fabricate houses. See also make1. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
manufacture (ˌmænjʊˈfæktʃə)
1.  to process or make (a product) from a raw material, esp as a large-scale operation using machinery
2.  (tr) to invent or concoct: to manufacture an excuse
3.  the production of goods, esp by industrial processes
4.  a manufactured product
5.  the creation or production of anything
[C16: from obsolete manufact hand-made, from Late Latin manūfactus, from Latin manus hand + facere to make]
n, —adj

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1560s, "something made by hand," from M.Fr. manufacture, from M.L. *manufactura, from L. manu, abl. of manus "hand" (see manual) + factura "a working," from pp. stem of facere "to perform" (see factitious). Sense of "process of manufacturing"
first recorded c.1600. The verb is attested from 1680s. Related: Manufactured; manufactures; manufacturing.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
People make ice cream, sell it, provide ingredients or manufacture the machines.
We no longer manufacture assets.
Someone in the house decided that when we all went into the business world, Jay
  was going to manufacture cream cheese.
Some folks need to grow up and stop taking offense at every minor slight they
  can manufacture.
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