A book, document, or other composition written by hand.
A typewritten or handwritten version of a book, an article, a document, or other work, especially the author's own copy, prepared and submitted for publication in print.
Handwriting.
[From Medieval Latin manūscrīptum, from neuter of manūscrīptus, handwritten : Latin manū, ablative of manus, hand; see man-2 in Indo-European roots + Latin scrīptus, past participle of scrībere, to write; see skrībh- in Indo-European roots.]