a combining form meaning “black,” used in the formation of compound words: melanocyte.
Also, especially before a vowel, melan-.

< Greek, combining form of mélās Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
melano- or (before a vowel) melan-
combining form
black or dark: melanin; melanism; melanocyte; melanoma
[from Greek melas black]
melan- or (before a vowel) melan-
combining form
[from Greek melas black]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

melano- or melan-
Black; dark: melanin.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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