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[muh-tas-tuh-sis] /məˈtæs tə sɪs/
noun, plural metastases
[muh-tas-tuh-seez] /məˈtæs təˌsiz/ (Show IPA)
  1. the transference of disease-producing organisms or of malignant or cancerous cells to other parts of the body by way of the blood or lymphatic vessels or membranous surfaces.
  2. the condition produced by this.
transformation (def 3).
Rhetoric. a rapid transition, as from one subject to another.
Physics. a change in position or orbit of an elementary particle.
Origin of metastasis
1580-90; < Greek metástasis a changing. See meta-, stasis
Related forms
[met-uh-stat-ik] /ˌmɛt əˈstæt ɪk/ (Show IPA),
metastatically, adverb Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the web for metastasis
  • metastasis is the spread of cancer to far away sites.
  • Many experiments showed that tumor growth and metastasis are angiogenesis-dependent.
  • He was found to have lung cancer and a single brain metastasis and was advised to have surgery, radiation and chemotherapy.
  • Cells that slough into the bloodstream can take hold at distant sites-and a metastasis is born.
  • As long as a single cancer cell escapes the destruction by metastasis to other part of body.
  • He was worried about metastasis, and recommended that the procedure be done immediately, but she balked.
  • metastasis new tumors that appear far from the original tumor.
British Dictionary definitions for metastasis


noun (pl) -ses (-ˌsiːz)
(pathol) the spreading of a disease, esp cancer cells, from one part of the body to another
a transformation or change, as in rhetoric, from one point to another
a rare word for metabolism
Derived Forms
metastatic (ˌmɛtəˈstætɪk) adjective
metastatically, adverb
Word Origin
C16: via Latin from Greek: transition
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for metastasis

1570s, originally in rhetoric, from Late Latin metastasis "transition," from Greek metastasis "a removing, removal; migration; a changing; change, revolution," from methistanai "to remove, change," from meta- "over, across" (see meta-) + histanai "to place, cause to stand," from PIE root *sta- "to stand" (see stet). A rhetorical term in Late Latin for "a sudden transition in subjects," medical use for "shift of disease from one part of the body to another" dates from 1660s in English. Related: Metastatic.

Online Etymology Dictionary, © 2010 Douglas Harper
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metastasis in Medicine

metastasis me·tas·ta·sis (mə-tās'tə-sĭs)
n. pl. me·tas·ta·ses (-sēz')

  1. Transmission of pathogenic microorganisms or cancerous cells from an original site to one or more sites elsewhere in the body, usually by way of the blood vessels or lymphatics.

  2. A secondary cancerous growth formed by transmission of cancerous cells from a primary growth located elsewhere in the body.

met'a·stat'ic (mět'ə-stāt'ĭk) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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metastasis in Science
A cancerous tumor formed by transmission of malignant cells from a primary cancer located elsewhere in the body.

metastasize verb
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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