[min-uh-skyool, mi-nuhs-kyool]
very small.
(of letters or writing) small; not capital.
written in such letters (opposed to majuscule ).
a minuscule letter.
a small cursive script developed in the 7th century a.d. from the uncial, which it afterward superseded.

1695–1705; < Latin minusculus smallish. See minus, -cule1

minuscular, adjective

minimal, minimize, minimum, minuscule, minutia (see usage note at the current entry).

Minuscule, from Latin minus meaning “less,” has frequently come to be spelled miniscule, perhaps under the influence of the prefix mini- in the sense “of a small size.” Although this newer spelling is criticized by many, it occurs with such frequency in edited writing that some consider it a variant spelling rather than a misspelling.
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
minuscule (ˈmɪnəˌskjuːl)
1.  a lower-case letter
2.  writing using such letters
3.  a small cursive 7th-century style of lettering derived from the uncial
4.  Compare majuscule relating to, printed in, or written in small letters
5.  very small
6.  (of letters) lower-case
[C18: from French, from Latin (littera) minuscula very small (letter), diminutive of minor]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

c.1730, "small (not capital) letter," from Fr. minuscule, from L. minuscula, in minuscula littera "slightly smaller letter," fem. of minusculus "rather less," dim. of minus "less" (see minus). Extended meaning of "extremely small" is first attested 1893.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Six minuscule species in many thousand is a small price to pay.
It can become the thinnest of wires and, potentially, electronic devices almost
  as minuscule as.
Consider the immense backlog, and what a minuscule percentage one can read in a
  lifetime of serious attention to reading.
The previous estimate showed a minuscule rise in output.
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