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mis-1

1.
a prefix applied to various parts of speech, meaning “ill,” “mistaken,” “wrong,” “wrongly,” “incorrectly,” or simply negating:
mistrial; misprint; mistrust.
Origin
Middle English; Old English mis(se)-; cognate with German miss-, Gothic missa- (see miss1; ); often replacing Middle English mes- < Old French < West Germanic *mis(s)-

mis-2

1.
variant of miso- before some vowels:
misanthrope.
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for mis-

mis-1

prefix
1.
wrong, bad, or erroneous; wrongly, badly, or erroneously: misunderstanding, misfortune, misspelling, mistreat, mislead
2.
lack of; not: mistrust
Word Origin
Old English mis(se)-; related to Middle English mes-, from Old French mes-; compare Old High German missa-, Old Norse mis-

mis-2

prefix
1.
a variant of miso-

miso-

combining form
1.
indicating hatred: misogyny
Word Origin
from Greek misos hatred
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for mis-

prefix meaning "bad, wrong," from Old English mis-, from Proto-Germanic *missa- "divergent, astray" (cf. Old Frisian and Old Saxon mis-, Middle Dutch misse-, Old High German missa-, German miß-, Old Norse mis-, Gothic missa-), perhaps literally "in a changed manner," and with a root sense of "difference, change" (cf. Gothic misso "mutually"), and thus from PIE *mit-to-, from root *mei- "to change" (see mutable); cf. Watkins.

Others [Barnhart] see in Proto-Germanic *missa- the stem of an ancient past participle, related to Old English missan "fail to hit" (see miss (v.)), which is from the same PIE root.

Productive as word-forming element in Old English (e.g. mislæran "to give bad advice, teach amiss"). In 14c.-16c. in a few verbs its sense began to be felt as "unfavorably" and was used as an intensive prefix with verbs already expressing negative feeling (e.g. misdoubt). Practically a separate word in Old and early Middle English (and often written as such). Old English also had an adjective (mislic "diverse, unlike, various") and an adverb (mislice "in various directions, wrongly, astray") derived from it, corresponding to German misslich (adj.).

in mischief, miscreant, etc., represents Old French mes- "bad, badly, wrong, wrongly," from Vulgar Latin minus-, from Latin minus "less" (see minus), which was not used as a prefix. Perhaps influenced in Old French by *miss-, the Frankish equivalent of mis- (1).

Online Etymology Dictionary, © 2010 Douglas Harper
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mis- in Medicine

mis- 1
pref.
Bad; badly; wrong; wrongly: misdiagnosis.

mis- 2
pref.
Variant of miso-.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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