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monoclonal antibody

noun, Biotechnology
1.
antibody produced by a laboratory-grown cell clone, either of a hybridoma or a virus-transformed lymphocyte, that is more abundant and uniform than natural antibody and is able to bind specifically to a single site on almost any chosen antigen or reveal previously unknown antigen sites: used as an analytic tool in scientific research and medical diagnosis and potentially important in the treatment of certain diseases.
Abbreviation: MAb.
Origin
1970-1975
1970-75
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for monoclonal-antibody

monoclonal antibody

/ˌmɒnəʊˈkləʊnəl/
noun
1.
an antibody, produced by a single clone of cells grown in culture, that is both pure and specific and is capable of proliferating indefinitely to produce unlimited quantities of identical antibodies: used in diagnosis, therapy, and biotechnology
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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monoclonal-antibody in Medicine

monoclonal antibody n.
Any of a class of highly specific antibodies produced by the clones of a single hybrid cell formed in the laboratory by the fusion of a B cell with a tumor cell and widely used in medical and biological research.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Article for monoclonal-antibody

monoclonal antibody

antibody produced artificially by a genetic engineering technique. Production of monoclonal antibodies was one of the most important techniques of biotechnology to emerge during the last quarter of the 20th century. When activated by an antigen, a circulating B cell multiplies to form a clone of plasma cells, each secreting identical immunoglobulin molecules. It is such immunoglobulins-derived from the descendants of a single B cell-that are called monoclonal antibodies.

Learn more about monoclonal antibody with a free trial on Britannica.com
Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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